A comprehensive collection of systems biology data characterizing the host response to viral infection.
Identifieur interne : 001715 ( Main/Exploration ); précédent : 001714; suivant : 001716A comprehensive collection of systems biology data characterizing the host response to viral infection.
Auteurs : Brian D. Aevermann [États-Unis] ; Brett E. Pickett [États-Unis] ; Sanjeev Kumar [États-Unis] ; Edward B. Klem [États-Unis] ; Sudhakar Agnihothram [États-Unis] ; Peter S. Askovich [États-Unis] ; Armand Bankhead [États-Unis] ; Meagen Bolles [États-Unis] ; Victoria Carter [États-Unis] ; Jean Chang [États-Unis] ; Therese R W. Clauss [États-Unis] ; Pradyot Dash [États-Unis] ; Alan H. Diercks [États-Unis] ; Amie J. Eisfeld [États-Unis] ; Amy Ellis [États-Unis] ; Shufang Fan [États-Unis] ; Martin T. Ferris [États-Unis] ; Lisa E. Gralinski [États-Unis] ; Richard R. Green [États-Unis] ; Marina A. Gritsenko [États-Unis] ; Masato Hatta [États-Unis] ; Robert A. Heegel [États-Unis] ; Jon M. Jacobs [États-Unis] ; Sophia Jeng [États-Unis] ; Laurence Josset [États-Unis] ; Shari M. Kaiser [États-Unis] ; Sara Kelly [États-Unis] ; G Lynn Law [États-Unis] ; Chengjun Li [République populaire de Chine] ; Jiangning Li [États-Unis] ; Casey Long [États-Unis] ; Maria L. Luna [États-Unis] ; Melissa Matzke [États-Unis] ; Jason Mcdermott [États-Unis] ; Vineet Menachery [États-Unis] ; Thomas O. Metz [États-Unis] ; Hugh Mitchell [États-Unis] ; Matthew E. Monroe [États-Unis] ; Garnet Navarro [États-Unis] ; Gabriele Neumann [États-Unis] ; Rebecca L. Podyminogin [États-Unis] ; Samuel O. Purvine [États-Unis] ; Carrie M. Rosenberger [États-Unis] ; Catherine J. Sanders [États-Unis] ; Athena A. Schepmoes [États-Unis] ; Anil K. Shukla [États-Unis] ; Amy Sims [États-Unis] ; Pavel Sova [États-Unis] ; Vincent C. Tam [États-Unis] ; Nicolas Tchitchek [États-Unis] ; Paul G. Thomas [États-Unis] ; Susan C. Tilton [États-Unis] ; Allison Totura [États-Unis] ; Jing Wang [États-Unis] ; Bobbie-Jo Webb-Robertson [États-Unis] ; Ji Wen [États-Unis] ; Jeffrey M. Weiss [États-Unis] ; Feng Yang [États-Unis] ; Boyd Yount [États-Unis] ; Qibin Zhang [États-Unis] ; Shannon Mcweeney [États-Unis] ; Richard D. Smith [États-Unis] ; Katrina M. Waters [États-Unis] ; Yoshihiro Kawaoka [États-Unis] ; Ralph Baric [États-Unis] ; Alan Aderem [États-Unis] ; Michael G. Katze [États-Unis] ; Richard H. Scheuermann [États-Unis]Source :
- Scientific data [ 2052-4463 ] ; 2014.
Descripteurs français
- KwdFr :
- Animaux, Bases de données factuelles, Biologie des systèmes, Collecte de données, Grippe humaine (physiopathologie), Grippe humaine (virologie), Humains, Infections à Orthomyxoviridae (physiopathologie), Infections à Orthomyxoviridae (virologie), Interactions hôte-pathogène, Souris, Virus de la grippe A (pathogénicité), Virus de la grippe A (physiologie).
- MESH :
- pathogénicité : Virus de la grippe A.
- physiologie : Virus de la grippe A.
- physiopathologie : Grippe humaine, Infections à Orthomyxoviridae.
- virologie : Grippe humaine, Infections à Orthomyxoviridae.
- Animaux, Bases de données factuelles, Biologie des systèmes, Collecte de données, Humains, Interactions hôte-pathogène, Souris.
English descriptors
- KwdEn :
- Animals, Data Collection, Databases, Factual, Host-Pathogen Interactions, Humans, Influenza A virus (pathogenicity), Influenza A virus (physiology), Influenza, Human (physiopathology), Influenza, Human (virology), Mice, Orthomyxoviridae Infections (physiopathology), Orthomyxoviridae Infections (virology), Systems Biology.
- MESH :
- pathogenicity : Influenza A virus.
- physiology : Influenza A virus.
- physiopathology : Influenza, Human, Orthomyxoviridae Infections.
- virology : Influenza, Human, Orthomyxoviridae Infections.
- Animals, Data Collection, Databases, Factual, Host-Pathogen Interactions, Humans, Mice, Systems Biology.
Abstract
The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate host-pathogen interactions at a systems level. This program generated 47 transcriptomic and proteomic datasets from 30 studies that investigate in vivo and in vitro host responses to viral infections. Human pathogens in the Orthomyxoviridae and Coronaviridae families, especially pandemic H1N1 and avian H5N1 influenza A viruses and severe acute respiratory syndrome coronavirus (SARS-CoV), were investigated. Study validation was demonstrated via experimental quality control measures and meta-analysis of independent experiments performed under similar conditions. Primary assay results are archived at the GEO and PeptideAtlas public repositories, while processed statistical results together with standardized metadata are publically available at the Influenza Research Database (www.fludb.org) and the Virus Pathogen Resource (www.viprbrc.org). By comparing data from mutant versus wild-type virus and host strains, RNA versus protein differential expression, and infection with genetically similar strains, these data can be used to further investigate genetic and physiological determinants of host responses to viral infection.
DOI: 10.1038/sdata.2014.33
PubMed: 25977790
Affiliations:
- République populaire de Chine, États-Unis
- Californie, Caroline du Nord, Maryland, Tennessee, Washington (État), Wisconsin
- Madison (Wisconsin)
- Université du Wisconsin à Madison
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Le document en format XML
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Eisfeld</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Ellis, Amy" sort="Ellis, Amy" uniqKey="Ellis A" first="Amy" last="Ellis">Amy Ellis</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Fan, Shufang" sort="Fan, Shufang" uniqKey="Fan S" first="Shufang" last="Fan">Shufang Fan</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Ferris, Martin T" sort="Ferris, Martin T" uniqKey="Ferris M" first="Martin T" last="Ferris">Martin T. Ferris</name><affiliation wicri:level="2"><nlm:affiliation>Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7264, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7264</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Gralinski, Lisa E" sort="Gralinski, Lisa E" uniqKey="Gralinski L" first="Lisa E" last="Gralinski">Lisa E. Gralinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290</wicri:regionArea><wicri:noRegion>North Carolina 27599-7290</wicri:noRegion></affiliation></author><author><name sortKey="Green, Richard R" sort="Green, Richard R" uniqKey="Green R" first="Richard R" last="Green">Richard R. Green</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Gritsenko, Marina A" sort="Gritsenko, Marina A" uniqKey="Gritsenko M" first="Marina A" last="Gritsenko">Marina A. Gritsenko</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Hatta, Masato" sort="Hatta, Masato" uniqKey="Hatta M" first="Masato" last="Hatta">Masato Hatta</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Heegel, Robert A" sort="Heegel, Robert A" uniqKey="Heegel R" first="Robert A" last="Heegel">Robert A. Heegel</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Jacobs, Jon M" sort="Jacobs, Jon M" uniqKey="Jacobs J" first="Jon M" last="Jacobs">Jon M. Jacobs</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Jeng, Sophia" sort="Jeng, Sophia" uniqKey="Jeng S" first="Sophia" last="Jeng">Sophia Jeng</name><affiliation wicri:level="1"><nlm:affiliation>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098</wicri:regionArea><wicri:noRegion>Oregon 97239-3098</wicri:noRegion></affiliation></author><author><name sortKey="Josset, Laurence" sort="Josset, Laurence" uniqKey="Josset L" first="Laurence" last="Josset">Laurence Josset</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kaiser, Shari M" sort="Kaiser, Shari M" uniqKey="Kaiser S" first="Shari M" last="Kaiser">Shari M. Kaiser</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kelly, Sara" sort="Kelly, Sara" uniqKey="Kelly S" first="Sara" last="Kelly">Sara Kelly</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Law, G Lynn" sort="Law, G Lynn" uniqKey="Law G" first="G Lynn" last="Law">G Lynn Law</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Li, Chengjun" sort="Li, Chengjun" uniqKey="Li C" first="Chengjun" last="Li">Chengjun Li</name><affiliation wicri:level="1"><nlm:affiliation>Division of Animal influenza, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences , Harbin, Heilongjiang Province 150001, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Division of Animal influenza, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences , Harbin, Heilongjiang Province 150001</wicri:regionArea><wicri:noRegion>Heilongjiang Province 150001</wicri:noRegion></affiliation></author><author><name sortKey="Li, Jiangning" sort="Li, Jiangning" uniqKey="Li J" first="Jiangning" last="Li">Jiangning Li</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Long, Casey" sort="Long, Casey" uniqKey="Long C" first="Casey" last="Long">Casey Long</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Luna, Maria L" sort="Luna, Maria L" uniqKey="Luna M" first="Maria L" last="Luna">Maria L. Luna</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Matzke, Melissa" sort="Matzke, Melissa" uniqKey="Matzke M" first="Melissa" last="Matzke">Melissa Matzke</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mcdermott, Jason" sort="Mcdermott, Jason" uniqKey="Mcdermott J" first="Jason" last="Mcdermott">Jason Mcdermott</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Menachery, Vineet" sort="Menachery, Vineet" uniqKey="Menachery V" first="Vineet" last="Menachery">Vineet Menachery</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Metz, Thomas O" sort="Metz, Thomas O" uniqKey="Metz T" first="Thomas O" last="Metz">Thomas O. Metz</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mitchell, Hugh" sort="Mitchell, Hugh" uniqKey="Mitchell H" first="Hugh" last="Mitchell">Hugh Mitchell</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Monroe, Matthew E" sort="Monroe, Matthew E" uniqKey="Monroe M" first="Matthew E" last="Monroe">Matthew E. Monroe</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Navarro, Garnet" sort="Navarro, Garnet" uniqKey="Navarro G" first="Garnet" last="Navarro">Garnet Navarro</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Neumann, Gabriele" sort="Neumann, Gabriele" uniqKey="Neumann G" first="Gabriele" last="Neumann">Gabriele Neumann</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Podyminogin, Rebecca L" sort="Podyminogin, Rebecca L" uniqKey="Podyminogin R" first="Rebecca L" last="Podyminogin">Rebecca L. Podyminogin</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Purvine, Samuel O" sort="Purvine, Samuel O" uniqKey="Purvine S" first="Samuel O" last="Purvine">Samuel O. Purvine</name><affiliation wicri:level="2"><nlm:affiliation>Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory , Richland, WA 99354, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory , Richland, WA 99354</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Rosenberger, Carrie M" sort="Rosenberger, Carrie M" uniqKey="Rosenberger C" first="Carrie M" last="Rosenberger">Carrie M. Rosenberger</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Sanders, Catherine J" sort="Sanders, Catherine J" uniqKey="Sanders C" first="Catherine J" last="Sanders">Catherine J. Sanders</name><affiliation wicri:level="2"><nlm:affiliation>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Schepmoes, Athena A" sort="Schepmoes, Athena A" uniqKey="Schepmoes A" first="Athena A" last="Schepmoes">Athena A. Schepmoes</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Shukla, Anil K" sort="Shukla, Anil K" uniqKey="Shukla A" first="Anil K" last="Shukla">Anil K. Shukla</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Sims, Amy" sort="Sims, Amy" uniqKey="Sims A" first="Amy" last="Sims">Amy Sims</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Sova, Pavel" sort="Sova, Pavel" uniqKey="Sova P" first="Pavel" last="Sova">Pavel Sova</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Tam, Vincent C" sort="Tam, Vincent C" uniqKey="Tam V" first="Vincent C" last="Tam">Vincent C. Tam</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Tchitchek, Nicolas" sort="Tchitchek, Nicolas" uniqKey="Tchitchek N" first="Nicolas" last="Tchitchek">Nicolas Tchitchek</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Thomas, Paul G" sort="Thomas, Paul G" uniqKey="Thomas P" first="Paul G" last="Thomas">Paul G. Thomas</name><affiliation wicri:level="2"><nlm:affiliation>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Tilton, Susan C" sort="Tilton, Susan C" uniqKey="Tilton S" first="Susan C" last="Tilton">Susan C. Tilton</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Totura, Allison" sort="Totura, Allison" uniqKey="Totura A" first="Allison" last="Totura">Allison Totura</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290</wicri:regionArea><wicri:noRegion>North Carolina 27599-7290</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Jing" sort="Wang, Jing" uniqKey="Wang J" first="Jing" last="Wang">Jing Wang</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Webb Robertson, Bobbie Jo" sort="Webb Robertson, Bobbie Jo" uniqKey="Webb Robertson B" first="Bobbie-Jo" last="Webb-Robertson">Bobbie-Jo Webb-Robertson</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Wen, Ji" sort="Wen, Ji" uniqKey="Wen J" first="Ji" last="Wen">Ji Wen</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Weiss, Jeffrey M" sort="Weiss, Jeffrey M" uniqKey="Weiss J" first="Jeffrey M" last="Weiss">Jeffrey M. Weiss</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Yang, Feng" sort="Yang, Feng" uniqKey="Yang F" first="Feng" last="Yang">Feng Yang</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Yount, Boyd" sort="Yount, Boyd" uniqKey="Yount B" first="Boyd" last="Yount">Boyd Yount</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Zhang, Qibin" sort="Zhang, Qibin" uniqKey="Zhang Q" first="Qibin" last="Zhang">Qibin Zhang</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mcweeney, Shannon" sort="Mcweeney, Shannon" uniqKey="Mcweeney S" first="Shannon" last="Mcweeney">Shannon Mcweeney</name><affiliation wicri:level="1"><nlm:affiliation>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098, USA ; Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health Sciences University , Portland, Oregon 97239-3098, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098, USA ; Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health Sciences University , Portland, Oregon 97239-3098</wicri:regionArea><wicri:noRegion>Oregon 97239-3098</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Richard D" sort="Smith, Richard D" uniqKey="Smith R" first="Richard D" last="Smith">Richard D. Smith</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Waters, Katrina M" sort="Waters, Katrina M" uniqKey="Waters K" first="Katrina M" last="Waters">Katrina M. Waters</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kawaoka, Yoshihiro" sort="Kawaoka, Yoshihiro" uniqKey="Kawaoka Y" first="Yoshihiro" last="Kawaoka">Yoshihiro Kawaoka</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName><placeName><settlement type="city">Madison (Wisconsin)</settlement><region type="state">Wisconsin</region></placeName><orgName type="university" n="3">Université du Wisconsin à Madison</orgName></affiliation></author><author><name sortKey="Baric, Ralph" sort="Baric, Ralph" uniqKey="Baric R" first="Ralph" last="Baric">Ralph Baric</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA ; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA ; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290</wicri:regionArea><wicri:noRegion>North Carolina 27599-7290</wicri:noRegion></affiliation></author><author><name sortKey="Aderem, Alan" sort="Aderem, Alan" uniqKey="Aderem A" first="Alan" last="Aderem">Alan Aderem</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Katze, Michael G" sort="Katze, Michael G" uniqKey="Katze M" first="Michael G" last="Katze">Michael G. 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Craig Venter Institute , La Jolla, CA 92037</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Kumar, Sanjeev" sort="Kumar, Sanjeev" uniqKey="Kumar S" first="Sanjeev" last="Kumar">Sanjeev Kumar</name><affiliation wicri:level="2"><nlm:affiliation>Northrop Grumman Information Systems, Health IT , Rockville, MD 20850, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Northrop Grumman Information Systems, Health IT , Rockville, MD 20850</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Klem, Edward B" sort="Klem, Edward B" uniqKey="Klem E" first="Edward B" last="Klem">Edward B. Klem</name><affiliation wicri:level="2"><nlm:affiliation>Northrop Grumman Information Systems, Health IT , Rockville, MD 20850, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Northrop Grumman Information Systems, Health IT , Rockville, MD 20850</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Agnihothram, Sudhakar" sort="Agnihothram, Sudhakar" uniqKey="Agnihothram S" first="Sudhakar" last="Agnihothram">Sudhakar Agnihothram</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Askovich, Peter S" sort="Askovich, Peter S" uniqKey="Askovich P" first="Peter S" last="Askovich">Peter S. Askovich</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Bankhead, Armand" sort="Bankhead, Armand" uniqKey="Bankhead A" first="Armand" last="Bankhead">Armand Bankhead</name><affiliation wicri:level="1"><nlm:affiliation>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098, USA ; Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health Sciences University , Portland, Oregon 97239-3098, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098, USA ; Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health Sciences University , Portland, Oregon 97239-3098</wicri:regionArea><wicri:noRegion>Oregon 97239-3098</wicri:noRegion></affiliation></author><author><name sortKey="Bolles, Meagen" sort="Bolles, Meagen" uniqKey="Bolles M" first="Meagen" last="Bolles">Meagen Bolles</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290</wicri:regionArea><wicri:noRegion>North Carolina 27599-7290</wicri:noRegion></affiliation></author><author><name sortKey="Carter, Victoria" sort="Carter, Victoria" uniqKey="Carter V" first="Victoria" last="Carter">Victoria Carter</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Chang, Jean" sort="Chang, Jean" uniqKey="Chang J" first="Jean" last="Chang">Jean Chang</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Clauss, Therese R W" sort="Clauss, Therese R W" uniqKey="Clauss T" first="Therese R W" last="Clauss">Therese R W. Clauss</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Dash, Pradyot" sort="Dash, Pradyot" uniqKey="Dash P" first="Pradyot" last="Dash">Pradyot Dash</name><affiliation wicri:level="2"><nlm:affiliation>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Diercks, Alan H" sort="Diercks, Alan H" uniqKey="Diercks A" first="Alan H" last="Diercks">Alan H. Diercks</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Eisfeld, Amie J" sort="Eisfeld, Amie J" uniqKey="Eisfeld A" first="Amie J" last="Eisfeld">Amie J. Eisfeld</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Ellis, Amy" sort="Ellis, Amy" uniqKey="Ellis A" first="Amy" last="Ellis">Amy Ellis</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Fan, Shufang" sort="Fan, Shufang" uniqKey="Fan S" first="Shufang" last="Fan">Shufang Fan</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Ferris, Martin T" sort="Ferris, Martin T" uniqKey="Ferris M" first="Martin T" last="Ferris">Martin T. Ferris</name><affiliation wicri:level="2"><nlm:affiliation>Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7264, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7264</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Gralinski, Lisa E" sort="Gralinski, Lisa E" uniqKey="Gralinski L" first="Lisa E" last="Gralinski">Lisa E. Gralinski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290</wicri:regionArea><wicri:noRegion>North Carolina 27599-7290</wicri:noRegion></affiliation></author><author><name sortKey="Green, Richard R" sort="Green, Richard R" uniqKey="Green R" first="Richard R" last="Green">Richard R. Green</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Gritsenko, Marina A" sort="Gritsenko, Marina A" uniqKey="Gritsenko M" first="Marina A" last="Gritsenko">Marina A. Gritsenko</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Hatta, Masato" sort="Hatta, Masato" uniqKey="Hatta M" first="Masato" last="Hatta">Masato Hatta</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Heegel, Robert A" sort="Heegel, Robert A" uniqKey="Heegel R" first="Robert A" last="Heegel">Robert A. Heegel</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Jacobs, Jon M" sort="Jacobs, Jon M" uniqKey="Jacobs J" first="Jon M" last="Jacobs">Jon M. Jacobs</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Jeng, Sophia" sort="Jeng, Sophia" uniqKey="Jeng S" first="Sophia" last="Jeng">Sophia Jeng</name><affiliation wicri:level="1"><nlm:affiliation>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098</wicri:regionArea><wicri:noRegion>Oregon 97239-3098</wicri:noRegion></affiliation></author><author><name sortKey="Josset, Laurence" sort="Josset, Laurence" uniqKey="Josset L" first="Laurence" last="Josset">Laurence Josset</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kaiser, Shari M" sort="Kaiser, Shari M" uniqKey="Kaiser S" first="Shari M" last="Kaiser">Shari M. Kaiser</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kelly, Sara" sort="Kelly, Sara" uniqKey="Kelly S" first="Sara" last="Kelly">Sara Kelly</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Law, G Lynn" sort="Law, G Lynn" uniqKey="Law G" first="G Lynn" last="Law">G Lynn Law</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Li, Chengjun" sort="Li, Chengjun" uniqKey="Li C" first="Chengjun" last="Li">Chengjun Li</name><affiliation wicri:level="1"><nlm:affiliation>Division of Animal influenza, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences , Harbin, Heilongjiang Province 150001, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Division of Animal influenza, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences , Harbin, Heilongjiang Province 150001</wicri:regionArea><wicri:noRegion>Heilongjiang Province 150001</wicri:noRegion></affiliation></author><author><name sortKey="Li, Jiangning" sort="Li, Jiangning" uniqKey="Li J" first="Jiangning" last="Li">Jiangning Li</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Long, Casey" sort="Long, Casey" uniqKey="Long C" first="Casey" last="Long">Casey Long</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Luna, Maria L" sort="Luna, Maria L" uniqKey="Luna M" first="Maria L" last="Luna">Maria L. Luna</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Matzke, Melissa" sort="Matzke, Melissa" uniqKey="Matzke M" first="Melissa" last="Matzke">Melissa Matzke</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mcdermott, Jason" sort="Mcdermott, Jason" uniqKey="Mcdermott J" first="Jason" last="Mcdermott">Jason Mcdermott</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Menachery, Vineet" sort="Menachery, Vineet" uniqKey="Menachery V" first="Vineet" last="Menachery">Vineet Menachery</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Metz, Thomas O" sort="Metz, Thomas O" uniqKey="Metz T" first="Thomas O" last="Metz">Thomas O. Metz</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mitchell, Hugh" sort="Mitchell, Hugh" uniqKey="Mitchell H" first="Hugh" last="Mitchell">Hugh Mitchell</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Monroe, Matthew E" sort="Monroe, Matthew E" uniqKey="Monroe M" first="Matthew E" last="Monroe">Matthew E. Monroe</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Navarro, Garnet" sort="Navarro, Garnet" uniqKey="Navarro G" first="Garnet" last="Navarro">Garnet Navarro</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Neumann, Gabriele" sort="Neumann, Gabriele" uniqKey="Neumann G" first="Gabriele" last="Neumann">Gabriele Neumann</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Podyminogin, Rebecca L" sort="Podyminogin, Rebecca L" uniqKey="Podyminogin R" first="Rebecca L" last="Podyminogin">Rebecca L. Podyminogin</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Purvine, Samuel O" sort="Purvine, Samuel O" uniqKey="Purvine S" first="Samuel O" last="Purvine">Samuel O. Purvine</name><affiliation wicri:level="2"><nlm:affiliation>Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory , Richland, WA 99354, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory , Richland, WA 99354</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Rosenberger, Carrie M" sort="Rosenberger, Carrie M" uniqKey="Rosenberger C" first="Carrie M" last="Rosenberger">Carrie M. Rosenberger</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Sanders, Catherine J" sort="Sanders, Catherine J" uniqKey="Sanders C" first="Catherine J" last="Sanders">Catherine J. Sanders</name><affiliation wicri:level="2"><nlm:affiliation>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Schepmoes, Athena A" sort="Schepmoes, Athena A" uniqKey="Schepmoes A" first="Athena A" last="Schepmoes">Athena A. Schepmoes</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Shukla, Anil K" sort="Shukla, Anil K" uniqKey="Shukla A" first="Anil K" last="Shukla">Anil K. Shukla</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Sims, Amy" sort="Sims, Amy" uniqKey="Sims A" first="Amy" last="Sims">Amy Sims</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Sova, Pavel" sort="Sova, Pavel" uniqKey="Sova P" first="Pavel" last="Sova">Pavel Sova</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Tam, Vincent C" sort="Tam, Vincent C" uniqKey="Tam V" first="Vincent C" last="Tam">Vincent C. Tam</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Tchitchek, Nicolas" sort="Tchitchek, Nicolas" uniqKey="Tchitchek N" first="Nicolas" last="Tchitchek">Nicolas Tchitchek</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Thomas, Paul G" sort="Thomas, Paul G" uniqKey="Thomas P" first="Paul G" last="Thomas">Paul G. Thomas</name><affiliation wicri:level="2"><nlm:affiliation>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Immunology, St. Jude Children's Research Hospital , Memphis, TN 38105-3678</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Tilton, Susan C" sort="Tilton, Susan C" uniqKey="Tilton S" first="Susan C" last="Tilton">Susan C. Tilton</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Totura, Allison" sort="Totura, Allison" uniqKey="Totura A" first="Allison" last="Totura">Allison Totura</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290</wicri:regionArea><wicri:noRegion>North Carolina 27599-7290</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Jing" sort="Wang, Jing" uniqKey="Wang J" first="Jing" last="Wang">Jing Wang</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Webb Robertson, Bobbie Jo" sort="Webb Robertson, Bobbie Jo" uniqKey="Webb Robertson B" first="Bobbie-Jo" last="Webb-Robertson">Bobbie-Jo Webb-Robertson</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Wen, Ji" sort="Wen, Ji" uniqKey="Wen J" first="Ji" last="Wen">Ji Wen</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Weiss, Jeffrey M" sort="Weiss, Jeffrey M" uniqKey="Weiss J" first="Jeffrey M" last="Weiss">Jeffrey M. Weiss</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Yang, Feng" sort="Yang, Feng" uniqKey="Yang F" first="Feng" last="Yang">Feng Yang</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Yount, Boyd" sort="Yount, Boyd" uniqKey="Yount B" first="Boyd" last="Yount">Boyd Yount</name><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Zhang, Qibin" sort="Zhang, Qibin" uniqKey="Zhang Q" first="Qibin" last="Zhang">Qibin Zhang</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mcweeney, Shannon" sort="Mcweeney, Shannon" uniqKey="Mcweeney S" first="Shannon" last="Mcweeney">Shannon Mcweeney</name><affiliation wicri:level="1"><nlm:affiliation>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098, USA ; Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health Sciences University , Portland, Oregon 97239-3098, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Oregon Clinical & Translational Research Institute , Portland, Oregon 97239-3098, USA ; Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health Sciences University , Portland, Oregon 97239-3098</wicri:regionArea><wicri:noRegion>Oregon 97239-3098</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Richard D" sort="Smith, Richard D" uniqKey="Smith R" first="Richard D" last="Smith">Richard D. Smith</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Waters, Katrina M" sort="Waters, Katrina M" uniqKey="Waters K" first="Katrina M" last="Waters">Katrina M. Waters</name><affiliation wicri:level="2"><nlm:affiliation>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Biological Sciences Division, Pacific Northwest National Laboratory , Richland, WA 99352</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kawaoka, Yoshihiro" sort="Kawaoka, Yoshihiro" uniqKey="Kawaoka Y" first="Yoshihiro" last="Kawaoka">Yoshihiro Kawaoka</name><affiliation wicri:level="2"><nlm:affiliation>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>School of Veterinary Medicine, Department of Pathobiological Sciences, Influenza Research Institute, University of Wisconsin-Madison , Madison, WI 53706</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName><placeName><settlement type="city">Madison (Wisconsin)</settlement><region type="state">Wisconsin</region></placeName><orgName type="university" n="3">Université du Wisconsin à Madison</orgName></affiliation></author><author><name sortKey="Baric, Ralph" sort="Baric, Ralph" uniqKey="Baric R" first="Ralph" last="Baric">Ralph Baric</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA ; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599-7400, USA ; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599-7290</wicri:regionArea><wicri:noRegion>North Carolina 27599-7290</wicri:noRegion></affiliation></author><author><name sortKey="Aderem, Alan" sort="Aderem, Alan" uniqKey="Aderem A" first="Alan" last="Aderem">Alan Aderem</name><affiliation wicri:level="2"><nlm:affiliation>Seattle Biomedical Research Institute , Seattle, WA 98109, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Biomedical Research Institute , Seattle, WA 98109</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Katze, Michael G" sort="Katze, Michael G" uniqKey="Katze M" first="Michael G" last="Katze">Michael G. Katze</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, University of Washington , Seattle, WA 98195, USA ; Washington National Primate Research Center, University of Washington , Seattle, WA 98195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Washington , Seattle, WA 98195, USA ; Washington National Primate Research Center, University of Washington , Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Scheuermann, Richard H" sort="Scheuermann, Richard H" uniqKey="Scheuermann R" first="Richard H" last="Scheuermann">Richard H. Scheuermann</name><affiliation wicri:level="2"><nlm:affiliation>J. Craig Venter Institute , La Jolla, CA 92037, USA ; Department of Pathology, University of California , San Diego, CA 92093, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>J. Craig Venter Institute , La Jolla, CA 92037, USA ; Department of Pathology, University of California , San Diego, CA 92093</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author></analytic><series><title level="j">Scientific data</title><idno type="ISSN">2052-4463</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Data Collection</term><term>Databases, Factual</term><term>Host-Pathogen Interactions</term><term>Humans</term><term>Influenza A virus (pathogenicity)</term><term>Influenza A virus (physiology)</term><term>Influenza, Human (physiopathology)</term><term>Influenza, Human (virology)</term><term>Mice</term><term>Orthomyxoviridae Infections (physiopathology)</term><term>Orthomyxoviridae Infections (virology)</term><term>Systems Biology</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Bases de données factuelles</term><term>Biologie des systèmes</term><term>Collecte de données</term><term>Grippe humaine (physiopathologie)</term><term>Grippe humaine (virologie)</term><term>Humains</term><term>Infections à Orthomyxoviridae (physiopathologie)</term><term>Infections à Orthomyxoviridae (virologie)</term><term>Interactions hôte-pathogène</term><term>Souris</term><term>Virus de la grippe A (pathogénicité)</term><term>Virus de la grippe A (physiologie)</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Grippe humaine</term><term>Infections à Orthomyxoviridae</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Influenza, Human</term><term>Orthomyxoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term><term>Infections à Orthomyxoviridae</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term><term>Orthomyxoviridae Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Data Collection</term><term>Databases, Factual</term><term>Host-Pathogen Interactions</term><term>Humans</term><term>Mice</term><term>Systems Biology</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Bases de données factuelles</term><term>Biologie des systèmes</term><term>Collecte de données</term><term>Humains</term><term>Interactions hôte-pathogène</term><term>Souris</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate host-pathogen interactions at a systems level. This program generated 47 transcriptomic and proteomic datasets from 30 studies that investigate in vivo and in vitro host responses to viral infections. Human pathogens in the Orthomyxoviridae and Coronaviridae families, especially pandemic H1N1 and avian H5N1 influenza A viruses and severe acute respiratory syndrome coronavirus (SARS-CoV), were investigated. Study validation was demonstrated via experimental quality control measures and meta-analysis of independent experiments performed under similar conditions. Primary assay results are archived at the GEO and PeptideAtlas public repositories, while processed statistical results together with standardized metadata are publically available at the Influenza Research Database (www.fludb.org) and the Virus Pathogen Resource (www.viprbrc.org). By comparing data from mutant versus wild-type virus and host strains, RNA versus protein differential expression, and infection with genetically similar strains, these data can be used to further investigate genetic and physiological determinants of host responses to viral infection. </div></front></TEI><affiliations><list><country><li>République populaire de Chine</li><li>États-Unis</li></country><region><li>Californie</li><li>Caroline du Nord</li><li>Maryland</li><li>Tennessee</li><li>Washington (État)</li><li>Wisconsin</li></region><settlement><li>Madison (Wisconsin)</li></settlement><orgName><li>Université du Wisconsin à Madison</li></orgName></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Aevermann, Brian D" sort="Aevermann, Brian D" uniqKey="Aevermann B" first="Brian D" last="Aevermann">Brian D. Aevermann</name></region><name sortKey="Aderem, Alan" sort="Aderem, Alan" uniqKey="Aderem A" first="Alan" last="Aderem">Alan Aderem</name><name sortKey="Agnihothram, Sudhakar" sort="Agnihothram, Sudhakar" uniqKey="Agnihothram S" first="Sudhakar" last="Agnihothram">Sudhakar Agnihothram</name><name sortKey="Askovich, Peter S" sort="Askovich, Peter S" uniqKey="Askovich P" first="Peter S" last="Askovich">Peter S. Askovich</name><name sortKey="Bankhead, Armand" sort="Bankhead, Armand" uniqKey="Bankhead A" first="Armand" last="Bankhead">Armand Bankhead</name><name sortKey="Baric, Ralph" sort="Baric, Ralph" uniqKey="Baric R" first="Ralph" last="Baric">Ralph Baric</name><name sortKey="Bolles, Meagen" sort="Bolles, Meagen" uniqKey="Bolles M" first="Meagen" last="Bolles">Meagen Bolles</name><name sortKey="Carter, Victoria" sort="Carter, Victoria" uniqKey="Carter V" first="Victoria" last="Carter">Victoria Carter</name><name sortKey="Chang, Jean" sort="Chang, Jean" uniqKey="Chang J" first="Jean" last="Chang">Jean Chang</name><name sortKey="Clauss, Therese R W" sort="Clauss, Therese R W" uniqKey="Clauss T" first="Therese R W" last="Clauss">Therese R W. Clauss</name><name sortKey="Dash, Pradyot" sort="Dash, Pradyot" uniqKey="Dash P" first="Pradyot" last="Dash">Pradyot Dash</name><name sortKey="Diercks, Alan H" sort="Diercks, Alan H" uniqKey="Diercks A" first="Alan H" last="Diercks">Alan H. 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Gritsenko</name><name sortKey="Hatta, Masato" sort="Hatta, Masato" uniqKey="Hatta M" first="Masato" last="Hatta">Masato Hatta</name><name sortKey="Heegel, Robert A" sort="Heegel, Robert A" uniqKey="Heegel R" first="Robert A" last="Heegel">Robert A. Heegel</name><name sortKey="Jacobs, Jon M" sort="Jacobs, Jon M" uniqKey="Jacobs J" first="Jon M" last="Jacobs">Jon M. Jacobs</name><name sortKey="Jeng, Sophia" sort="Jeng, Sophia" uniqKey="Jeng S" first="Sophia" last="Jeng">Sophia Jeng</name><name sortKey="Josset, Laurence" sort="Josset, Laurence" uniqKey="Josset L" first="Laurence" last="Josset">Laurence Josset</name><name sortKey="Kaiser, Shari M" sort="Kaiser, Shari M" uniqKey="Kaiser S" first="Shari M" last="Kaiser">Shari M. Kaiser</name><name sortKey="Katze, Michael G" sort="Katze, Michael G" uniqKey="Katze M" first="Michael G" last="Katze">Michael G. 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Sanders</name><name sortKey="Schepmoes, Athena A" sort="Schepmoes, Athena A" uniqKey="Schepmoes A" first="Athena A" last="Schepmoes">Athena A. Schepmoes</name><name sortKey="Scheuermann, Richard H" sort="Scheuermann, Richard H" uniqKey="Scheuermann R" first="Richard H" last="Scheuermann">Richard H. Scheuermann</name><name sortKey="Shukla, Anil K" sort="Shukla, Anil K" uniqKey="Shukla A" first="Anil K" last="Shukla">Anil K. Shukla</name><name sortKey="Sims, Amy" sort="Sims, Amy" uniqKey="Sims A" first="Amy" last="Sims">Amy Sims</name><name sortKey="Smith, Richard D" sort="Smith, Richard D" uniqKey="Smith R" first="Richard D" last="Smith">Richard D. Smith</name><name sortKey="Sova, Pavel" sort="Sova, Pavel" uniqKey="Sova P" first="Pavel" last="Sova">Pavel Sova</name><name sortKey="Tam, Vincent C" sort="Tam, Vincent C" uniqKey="Tam V" first="Vincent C" last="Tam">Vincent C. Tam</name><name sortKey="Tchitchek, Nicolas" sort="Tchitchek, Nicolas" uniqKey="Tchitchek N" first="Nicolas" last="Tchitchek">Nicolas Tchitchek</name><name sortKey="Thomas, Paul G" sort="Thomas, Paul G" uniqKey="Thomas P" first="Paul G" last="Thomas">Paul G. Thomas</name><name sortKey="Tilton, Susan C" sort="Tilton, Susan C" uniqKey="Tilton S" first="Susan C" last="Tilton">Susan C. Tilton</name><name sortKey="Totura, Allison" sort="Totura, Allison" uniqKey="Totura A" first="Allison" last="Totura">Allison Totura</name><name sortKey="Wang, Jing" sort="Wang, Jing" uniqKey="Wang J" first="Jing" last="Wang">Jing Wang</name><name sortKey="Waters, Katrina M" sort="Waters, Katrina M" uniqKey="Waters K" first="Katrina M" last="Waters">Katrina M. Waters</name><name sortKey="Webb Robertson, Bobbie Jo" sort="Webb Robertson, Bobbie Jo" uniqKey="Webb Robertson B" first="Bobbie-Jo" last="Webb-Robertson">Bobbie-Jo Webb-Robertson</name><name sortKey="Weiss, Jeffrey M" sort="Weiss, Jeffrey M" uniqKey="Weiss J" first="Jeffrey M" last="Weiss">Jeffrey M. Weiss</name><name sortKey="Wen, Ji" sort="Wen, Ji" uniqKey="Wen J" first="Ji" last="Wen">Ji Wen</name><name sortKey="Yang, Feng" sort="Yang, Feng" uniqKey="Yang F" first="Feng" last="Yang">Feng Yang</name><name sortKey="Yount, Boyd" sort="Yount, Boyd" uniqKey="Yount B" first="Boyd" last="Yount">Boyd Yount</name><name sortKey="Zhang, Qibin" sort="Zhang, Qibin" uniqKey="Zhang Q" first="Qibin" last="Zhang">Qibin Zhang</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Li, Chengjun" sort="Li, Chengjun" uniqKey="Li C" first="Chengjun" last="Li">Chengjun Li</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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